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MRI Guided Drug Delivery at AmplifyBio
for GLP Studies

AmplifyBio offers cutting-edge solutions for central nervous system (CNS) drug delivery in our GLP preclinical laboratory, leveraging advanced imaging technologies and surgical expertise. Our state-of-the-art facilities and skilled veterinary team ensure precise, safe, and effective delivery of therapeutics into the CNS, enhancing the outcomes of pharmacological studies and advancing neuroscience research. AmplifyBio NHPs are onsite and available for rapid study initiation.

The AmplifyBio Difference

Rapid Turnaround

Our facilities are always ready for immediate use, ensuring quick response to client needs.

 

Comprehensive Support

From patient monitoring to advanced surgical techniques, we provide complete support to ensure the success of your studies.

Collaborative Approach

We work closely with clients to tailor our services to their specific requirements, enhancing the value and impact of their research.

Advanced Imaging and Targeting Technologies

We are excited to introduce our mobile MRI unit, integrated with ClearPoint® Navigation System. This advanced system hardware and software offers:

  • Enhanced Precision: Accurately targets specific anatomical landmarks and safe trajectories within the intracranial space.
  • Increased Safety: Ensures procedures are conducted with minimal risk to animal models.
  • Strategic Dosing: Facilitates advanced dosing routes directly into the CNS, improving the effectiveness of therapeutic delivery.
  • Improved Outcomes: Enhances the reliability of surgical procedures, benefiting research outcomes and client satisfaction.

Mobile MRI Unit and ClearPoint Neuro

Our collaboration with ClearPoint Neuro and the introduction of our mobile MRI unit provide unparalleled capabilities:

  • Real-time Imaging and Navigation: ClearPoint® Navigation System integrated with the MRI unit allows for real-time imaging and precise navigation during surgical procedures and MRI dosing.
  • Minimally Invasive Procedures: The advanced imaging techniques reduce the need for invasive procedures, minimizing risks and recovery times for animal models.
  • Versatility in Applications: The mobile MRI unit supports a variety of CNS drug delivery methods, from intracerebral to intrathecal injections, enhancing the scope of research possibilities.

AmplifyBio Additional Services

Preclinical CRO services play a crucial role in drug development by conducting studies and experiments on potential therapeutics before they advance to clinical trials. AmplifyBio offers a wide-range of preclinical CRO services including:

ADOC

AmplifyBio Discovery, Optimization, and Characterization

An outsourced R&D solution for benchmarking next-generation therapeutics
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ASET

AmplifyBio Safety, Efficacy and Toxicology

A preclinical CRO built for the future on a decades-long foundation of expertise and experience
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AMEC

AmplifyBio Manufacturing Enablement Center

A manufacturing partnership for multiple modalities, offered in flexible contract staffing models to fit varied requirements
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Contact Us

Comprehensive service programs for the development of Cell and Gene Therapy (CGT), mRNA, and other advanced therapies from concept to commercial. Offering expertise and support in discovery, characterization, preclinical CRO safety testing, and scalable manufacturing available in an integrated, innovation-rich environment that goes beyond the value proposition offered by traditional CDMO and PDMO contract models.

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